中文
Short name：m-AST
Detection method：Immunosuppression
Packaging specifications：Various
①: The product packaging is suitable for mainstream models such as Hitachi, Abbott, Siemens, Roche, Beckman, Toshiba, Deere, Mindray, Kehua and so on.
②: High sensitivity, high specificity and strong anti-interference ability.
Clinical Significance
Aspartic aminotransferase has two isoenzymes, namely, the cytoplasmic aspartic aminotransferase (s-ast) and the mitochondrial aspartic aminotransferase (m-ast), which are widely found in liver, heart, skeletal muscle, kidney and other tissues of animals or humans, especially the heart and liver.In general, the activity of s-ast in serum is much higher than that of m-ast, and the activity of m-ast accounts for less than 10% of the total AST activity. However, when there is liver damage, especially when there is necrosis of heart and liver cells, the activity of m-ast is significantly increased.
Inspecting Principle
m-AST
L-Aspartic acid+α-Ketodioic acid一→Oxaloacetate+glutamic acid.
MDH
Oxaloacetate+α-Ketoglutarate一→L-Malic acid+NAD﹢.
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